Elevated microRNA-125b inhibits cytotrophoblast invasion and impairs endothelial cell function in preeclampsia
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چکیده
منابع مشابه
microRNA-125b inhibits cell migration and invasion by targeting matrix metallopeptidase 13 in bladder cancer
The expression of microRNA-125b (miR-125b) has been investigated in many human cancers. It has been demonstrated to be downregulated in certain types of cancer, such as bladder cancer, thyroid anaplastic carcinomas, squamous cell carcinoma of the tongue, hepatocellular carcinoma, ovarian and breast cancer. In the present study, we examined the effects of miR-125b on bladder cancer cell migratio...
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The lack of broad-spectrum anti-acute liver failure (ALF) therapeutic agents contributes to ALF-related mortality. MicroRNAs (miRNAs) are suggested to be potent serum biomarkers for ALF, but their functional and therapeutic relevance in ALF are unclear. Here we show an unbiased approach, using two complementary miRNA screens, to identify miRNAs that can attenuate ALF. We identify miR-125b-5p as...
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ژورنال
عنوان ژورنال: Cell Death Discovery
سال: 2020
ISSN: 2058-7716
DOI: 10.1038/s41420-020-0269-0